- SOD = Superoxide Dismutase. The enzyme with the highest antioxidant capacity in nature.
- Raw material TetraSOD® from natural phytoplankton grown under controlled conditions.
- There is no more potent antioxidant. Biological activity ≥30,000 IU.
- Tested and validated by combined ORAC 5.0 and CAA tests in certified laboratories.
- It contains the most effective dose for the broad spectrum of effectiveness: 25mg / 750 U of SOD.
- Formula supplemented with synergistic antioxidant vitamins: Vitamin C and natural Vitamin E.
- Natural SOD from phytoplankton grown under controlled conditions. Never harvested.
- Product suitable for vegan diets. Gluten-free and free of Genetically Modified Organisms.

Nature’s most powerful antioxidant: SOD
SOD (Superoxide Dismutase) (TetraSOD®️) 25mg by EssentialSeries is a food supplement made from the enzyme Superoxide Dismutase, better known as SOD, originating from natural sources, unlike most SODs on the market that are developed from synthesis or genetically modified organisms; a practice that we at HSN reject.
TetraSOD®️, developed by the company Fitoplancton Marino SL, is the result of several decades of research, development, and innovation to obtain the best ultra-purified Superoxide Dismutase enzyme from natural plankton grown in sealed environments for maximum potency, without genetic alteration of the plankton to artificially alter the power of SOD.
Of national origin, TetraSOD®️ is developed from the Plankton species discovered in the heart of the Doñana Natural Park, located in the province of Huelva, close to Cadiz and Seville.
What is sod and why should i incorporate it into my diet?
SOD is an enzyme in the human body, but it is not just limited to us:
Due to the biological activity that the antioxidant enzyme possesses, catalysing the conversion of the superoxide anion into H2O2 for its subsequent splitting into water and oxygen, all living organisms have it… Yes, yes, you read that right, from simple prokaryotic cells to the human being, which is the pinnacle of evolutionary development, they all have Superoxide Dismutase acting within them.
Superoxide Dismutase is a metalloenzyme, so it is always found in combination with a ‘metalloid’ element such as Iron, Nickel, Zinc, etc. No one expression is superior to the other, but the combination of different versions of this metalloenzyme is a superior option to any one of them.
The phytoplankton species used for the development of TetraSOD®️ is the best possible for obtaining pure Superoxide Dismutase of the highest quality, since in the microalgae Tetraselmis chuii 3 different genes have been identified that encode the expression of 3 SOD isoforms, these being: Mn, Cu-Zn, and Ni.
HSN brings you the most powerful sod thanks to the combined expression of 3 isoforms of this indispensable enzyme!
TetraSOD® and HSN – An unbeatable combination!
At HSN, we never stop innovating, and part of this innovation is the relentless search for important and interesting new compounds to complement the nutritional needs of our customers.
We had been investigating the SOD for years, but… We were not convinced… We found a lot of synthetic SOD that did not fit what we were looking for, and the natural SOD did not meet our purity and activity criteria, not to mention that most of the natural SOD sold on the market come from species with Genetically Modified Organisms… In short, a project that we were on the verge of shutting down.
But we found Marine Phytoplankton! A national company known for its high-quality standards, they have the best SOD raw material you can get, and this is TetraSOD®️.

After our tests, product analysis, and documentary analysis, we validated the raw material as what we had been searching for years and we have crowned this process with the development of the product you are now in.
You can be sure that you are dealing with the ultimate SOD product: the best raw material, an effective dose, and a complementary formulation thanks to the action of the added vitamins that make there is nothing better on the market.
SOD origin: Phytoplankton
SOD is, as indicated above, an enzyme present in all existing life forms, even the simplest, but not all of them are equally effective in obtaining an ultra-pure presentation of the compound.
Phytoplankton microalgae are the perfect source for extracting this enzyme.
The phytoplankton is developed under controlled culture conditions that allow the raw material to be properly treated to obtain the pure enzyme in various isoforms, of maximum purity so that its efficacy is guaranteed to be the highest available on the market.
TetraSOD®️ is Superoxide Dismutase extracted solely and exclusively from natural phytoplankton.

The importance of cultivation (never harvesting)
The microalgae used to prepare TetraSOD®️ are not just any plankton, as only certain species are optimal for the extraction of high-purity SOD; among all of them, one stands out above the rest by far: Tetraselmis chuii.
This particular species has been obtained for the first time from the extraction of the lakes of the Veta La Palma estate, an authentic natural paradise and maximum expression of biodiversity where under its waters is found the greatest environmental treasure: Tetraselmis chuii as part of the marine phytoplankton species.
From the collection of this species and its validation as the most suitable source for the highest potency SOD, a unique proprietary cultivation system has been developed and protected under TetraSOD’s patent rights, ensuring that there is no other SOD like it on the market.
Phytoplankton is not collected from free environments but is collected from internal culture, controlled under specific conditions of environmental exposure to factors such as Co2, sunlight, and nutrients in the culture medium.
A key patented technology for microalgae with a high level of SOD, the result of research and development by Fitoplancton Marino S.L., unique in the world, is applied to these conditions to obtain the highest purity SOD possible.
Harvesting and subsequent centrifugation + freeze-drying results in TetraSOD®️, a raw material that is unique in the world.
Guaranteed antioxidant activity: Find out more
The antioxidant potency of a compound can be measured, most commonly by applying a system known as ‘ORAC measurement’ (Oxygen Radical Absorbance Capacity) which is used as an international reference value and measure to establish how antioxidant a product is.
Just for reference, the antioxidant power of TetraSOD®️ is 30000 U per gram of dry weight, while that of other microalgae is around 1000 U, i.e., it accumulates up to 30 times more SOD activity than any other marine phytoplankton strain on the market. Incredible, isn’t it?
The ORAC value of TetraSOD is almost 10 times higher than that of Goji berries, almost 15 times higher than grapes, and more than 25 times higher than antioxidant-rich citrus fruits such as lemons or kiwi fruit.
Values from scientific studies carried out with TetraSOD show:
Parameter | Value |
SOD activity | ≥30000 UI |
AAC (Antioxidant Capacity in Live Cells) | 38,94 µmole QE |
ORAC (Oxygen Radical Absorption Capacity) | 38,94 µmole TE/100g |
Unbeatable values!

Enhanced with HSN’s exclusive formula: High in Vitamins C and E
At HSN we were not going to limit ourselves to making our product exclusively with TetraSOD®️, even if SOD is the star compound of the product, we had to improve it!
And we have achieved this by adding the 2 vitamins with the highest antioxidant capacity: Vitamin C and vitamin E.
Both vitamins contribute to the protection of cells against oxidative damage.
At HSN we have used the best presentations of these vitamins so that their absorption is maximum, and the body can take full advantage of them:
- Ascorbic acid (pure vitamin C).
- D-Alpha-tocopheryl acid succinate (natural vitamin E).
Both vitamins are present in significant quantities, in fact, the product provides 100% of the minimum daily requirement of vitamin C and almost one-third of vitamin E.
Why 25 mg? Here are the reasons for the best dose
The minimum dose of TetraSOD®️, according to the company’s internal research, is as little as 4.67mg. At this dose, you get enough for a basic antioxidant effect, but the properties of TetraSOD®️ do not stop there.
Research carried out with athletes shows that the most effective amount of TetraSOD®️ to take advantage of the full spectrum of the product’s properties is 25mg.
At HSN we have reviewed the methodology of the internal studies of Marine Phytoplankton and have validated the 25mg dose as the most appropriate amount for the development of our supplement, as its effectiveness is maximum at this amount, and its safety is total.
Trust only hsn which guarantees you the best concentration of its products.
I am interested in antioxidants, should i choose this one?
There are many antioxidants on the food supplement market, and in the following section, we are going to recommend other options that you should consider for your daily combo.
The differences between them all lie in concentration, purity, and personal preference based on experience.
SOD (Superoxide Dismutase) (TetraSOD®️) 25mg is ideal for people:
- Exposed to high levels of oxidative damage. E.g.: First aiders that are heavily exposed to the sun.
- Athletes who train very frequently during the week. To be used after training together with Evorecovery, a recovery formula thanks to its supply of nutrients, such as carbohydrates.
- Elderly people. Ideal to combine with products such as Red Yeast Rice with Coenzyme Q10.
What if i want to use more antioxidants, can i? Here are the recommendations of the HSN specialists!
Our experts recommend combining TetraSOD®️ with other antioxidants only if you need an extra-potent load of antioxidants, as this product itself is highly potent.
The most suitable combinations are:
- NADH (Panmol®️).
- PQQ.
- Ubiquinol (Kaneka™).
- Spirulina 1000mg.
Bibliographical References
- Fukai, T., & Ushio-Fukai, M. (2011). Superoxide dismutases: Role in redox signaling, vascular function, and diseases. Antioxidants and Redox Signaling, 15(6), 1583–1606.
- Younus, H. (2018). Therapeutic potentials of superoxide dismutase. International Journal of Health Sciences, 12(3), 88–93.
- Gil-Cardoso, K., Del Bas, J. M., Caimari, A., Lama, C., Torres, S., Mantecón, L., & Infante, C. (2022). TetraSOD®, a Unique Marine Microalgae Ingredient, Promotes an Antioxidant and Anti-Inflammatory Status in a Metabolic Syndrome-Induced Model in Rats. Nutrients, 14(19).
- Spoelstra-De Man, A. M. E., Elbers, P. W. G., & Oudemans-Van Straaten, H. M. (2018). Vitamin C: Should we supplement? Current Opinion in Critical Care, 24(4), 248–255.
- Reboul, E. (2017). Vitamin e bioavailability: Mechanisms of intestinal absorption in the spotlight. Antioxidants, 6(4).